GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy
AimsIndividuals with lipodystrophies typically suffer from metabolic disease linked to adipose tissue dysfunction including lipoatrophic diabetes.In the most severe forms of lipodystrophy, congenital generalised lipodystrophy, adipose tissue may be almost entirely absent.Better therapies for affected individuals are urgently needed.Here we performe